Prescot Church stands on a hill, 8 miles east of Liverpool, just off the main A57 Liverpool-St Helens road. It is easily reached from the motorway network (Junction 6 on the M62 and Junction 1 on the M57). There are car parks close to the church.
All buses between Liverpool and St Helens (10, 10A, 10X, ) stop close to the church and run every 30 minutes on Sundays (much more frequently on weekdays). There are also direct services from Warrington, Runcorn, Widnes, Kirkby and Huyton.
Prescot station is served by regular trains between Liverpool Lime Street and St Helens, Wigan and Preston. The church is a 10 minute walk from the station.